Dry eyes can be exacerbated by systemic antihypertensive medication.

Dry eye disease (DED) is a frequent problem in ophthalmology, causing considerable morbidity. DED is a multifactorial disease and requires a comprehensive approach in identifying the potential contributing factors. Often, clinicians overlook the fact that systemic medications are a cause of dry eye. We report two patients who developed symptoms and signs of DED secondary to systemic antihypertensive medication that improved following cessation of systemic medication.

Scott Med J. 2012 May;57(2):121.
Sagili S, Malhotra R.
Corneo Plastic Unit, Queen Victoria Hospital, East Grinstead, UK.