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Hello,
There's a new antidepressant coming out later this year - called Fetzima (levomilnacipran).
Fetzima is a chemical cousin of Savella (Milnacipran)
Fetzima is only approved for treatment of Major Depression.
Link to Fetzima:
https://fetzima.com
Savella is only approved for treatment of fibromyalgia.
http://www.savella.com
Not sure how much better Fetzima will be over other SNRIs like Cymbalta
here's the specs about it in comparison to other SNRIs (and, see attached paper)
Venlafaxine - has a 30-fold greater specificity for serotonin than norepinephrine
Cymbalta - has a 10 fold greater specificity for serotonin than norepinephrine
Milnacipran(Savella) - has a 1:1 relationship regarding serotonin and norepinephrine (prefers each the same ratio)
Levomilnacipran (fetzima) has a 1:2 relationship between preferring serotonin and norepinephrine, respectively.
Link to abstract about Fetzima -
http://www.ncbi.nlm.nih.gov/pubmed/23499664
There's a new antidepressant coming out later this year - called Fetzima (levomilnacipran).
Fetzima is a chemical cousin of Savella (Milnacipran)
Fetzima is only approved for treatment of Major Depression.
Link to Fetzima:
https://fetzima.com
Savella is only approved for treatment of fibromyalgia.
http://www.savella.com
Not sure how much better Fetzima will be over other SNRIs like Cymbalta
here's the specs about it in comparison to other SNRIs (and, see attached paper)
Venlafaxine - has a 30-fold greater specificity for serotonin than norepinephrine
Cymbalta - has a 10 fold greater specificity for serotonin than norepinephrine
Milnacipran(Savella) - has a 1:1 relationship regarding serotonin and norepinephrine (prefers each the same ratio)
Levomilnacipran (fetzima) has a 1:2 relationship between preferring serotonin and norepinephrine, respectively.
Link to abstract about Fetzima -
http://www.ncbi.nlm.nih.gov/pubmed/23499664