Doxy for MGD

[mbperso]

I experienced doxy 100mg/day, 1 month out 2, for a few months => very effective on me and no side effects.
2 years ago I experienced Azyter drops and it seemed to work well.
From what I read Azithromycin pills are more effective and with no side effects

[deep_dry_eye]

I thinking of talking to my Doc on the 12th about using something to stop my glands reblocking.

Any thoughts on minocycline, it seems to have a positive effect on the quality of the oils produced.

I've found a number of studies, one below and it seems to be more gentle on the stomach.

https://www.contactlensjournal.com/a...020-5/abstract

minocycline and doxy belong to the same class of antibiotics, they should have similar effects. personally i still find azithromycin to be the best (ive tried doxy as well).

[quattroboy]

I thinking of talking to my Doc on the 12th about using something to stop my glands reblocking.

Any thoughts on minocycline, it seems to have a positive effect on the quality of the oils produced.

I've found a number of studies, one below and it seems to be more gentle on the stomach.

https://www.contactlensjournal.com/a...020-5/abstract

[deep_dry_eye]

You can try Azithromycin instead, Azithromycin is usually softer on the stomach, and is more effective for MGD. It's less prescribed because there is no sub-antibiotic dosage (i.e., for doxy, the dosage prescribed usually 20-40mg vs say 150mg which is used for infections).

Topical Azithromycin is also very effective, and personally its the most effective drug I've ever used. Azyter is topical Azithromycin w/o preservatives and available in the EU and various countries in Asia. It's also super cheap as well. I recommend you giving that a try if you can get access to it. Topical Azithromycin can flush out your glands and convert your thick secretions and liquify them.

I’d do whatever your dr says. My personal protocol is to stay on 100mg twice a day as long as possible up to a year. Then taper to a lower maintenance dose of 50mg indefinitely. I am exactly like you, my stomach does very bad with antibiotics. I’d love to say I’ve had zero side effects but I can’t. My only real side effect is nausea. After a couple months on the drug, taking the pill makes me sick now for about an hour. I still think it’s wirth it. Doxy and steroids are the only two drugs that really unblocked my glands and healed my lids. So I think it’s a crucial piece of the puzzle. Nothing legitimately helped until I took doxy. So I get your apprehension, but honestly, I would do it. You have very little to lose and a lot to gain. Good luck, hope you start feeling better on the doxy.

[Signe]

I have MGD and severe dry eyes. I have tried everything that is available for dry eyes (IPL, Lipiflow, Restasis, Ikervis, all kind of eye drops, Blephasteam googles and lid massage, lid hygiene, coconut oil, castor oil, omega 3, vitamins, drinking plenty of water, testosterone cream, Manuka honey drops etc etc), but I have not tried doxy yet because my stomach usually does not tolerate antibiotics at all. My glands are totally blocked and my Dr. recommends doxy for 3 months. Has anyone experienced that the effect from doxy is long term? I am worried that I will go through 3 months with plenty of side effects from the doxy and that the eventual result only is temporary. Any advice?