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Insulin-like growth factor - the next breakthrough?

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  • Insulin-like growth factor - the next breakthrough?

    The results of a recent study at Schepens Institute. They used IGF in combination with topical azithromycin, already available as Azasite or Azyter:

    "In summary, our study has demonstrated that the combination of AZM and IGF-1 promotes lipid accumulation including both neutral and polar lipids, while preserving a normal cell proliferation in IHMGECs. These effects involve the modulation of SREBP-1 and cyclin B1, respectively. We believe this combination regime may represent a unique and effective treatment of MGD when used topically on the ocular surface or eyelid."

    It is in the very early phases however. Here is the full text of the article:

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160077/
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