GPC and contact lenses

[20/20_Hindsight]

Dear Dr. G;

I have always gotten GPC with all soft contact lenses. I have not been able to tolerate an RGP long enough to know if this also was the case. (All of this is prior to LASIK).

Can you please explain:

1. The mechanism of GPC? (what is it, what causes it and why some people get it and others do not.)

2. Is it a common occurrence with RGPs (or mini sclerals)?

3. How is it treated and how do we avoid it?

Thank you for your time and contributions to this forum!

[DrG]

GPC, or giant papillary conjunctivitis, is a condition that affects the tissue on the inner side of the upper eyelid. The symptoms are intense itching, mucus discharge, and a foreign body sensation. The cause is friction between the eyelid and a contacts lens against a backdrop of seasonal allergies. Soft lenses are more likely to cause GPC than RGP lenses. Dry eyes are more susceptible because of a lack of lubricating tears. Because buildup on the lens appears to be a contributing factor, some type of daily disposable lens is ideal -- or switching to some type of RGP lens with a low edge profile. Pharmaceutical treatments include mild topical steroids, and/or a mast cell stabilizer like Patanol.

GPC will go away in the absence of contact lens wear, but it can usually be controlled enough to permit a patient to continue wearing lenses.