I started a thread a month ago, after my trip to see dr rosenthal in boston, about my new diagnosis of corneal nerve damage and resulting hypersensitivity and neuropathy.
I have found another source pointing to corneal nerve neuropathy
I am wanting to get more people aware of this problem because a lot more of us may have this than is realized, and we need to learn root causes instead of just only trying to treat what we can see on the surface (MGD/BLEPH/DES)
here is a paper from University of Helsinki in Helsinki, Finland describing corneal neuropathy after damage from surgery like lasik.
CORNEAL NERVES IN REFRACTIVE
SURGERY AND DRY EYE
heres the link to the main article. I put excerpts of the most important parts down below...
https://www.doria.fi/bitstream/handl...pdf?sequence=1
Here are some important excerpts
"Presumably, at least part of the symptoms of “LASIKassociated
dry eye” are derived from aberrantly regenerated and abnormally functioning corneal
nerves. Thus, they may represent a form of corneal neuropathy or “phantom pain” rather than
conventional dry eye."
""""Corneal refractive surgery (PRK and LASIK) severs corneal sensory nerves, impairing corneal sensitivity and function. Corneal nerve regeneration begins shortly, but the original fine nerve architecture may never be completely restored. Patients experience varying degrees of dry eye symptoms for a 1to 6month period following refractive surgery. Occasionally, extensive dry eye symptoms or even ocular pain may persist for years, with or without dry eye signs. On the other hand, patients may have clinical signs compatible with dry eye, but present with minimal or no symptoms."""""
'''''Secretion of tear fluid is also regulated by the corneal nerves
forming the afferent loop of the cornealacrimal
gland reflex arc. Several systemic and corneal
disorders as well as ocular surgery may damage the corneal nerves and impair their function.
Consequently, the regulation of epithelial cell and keratocyte metabolism and also tear
formation and corneal sensitivity are disturbed until innervation is restored.''''
"""""""changes in corneal curvature
may interfere with even tear distribution, but the mechanical rubbing due to the anatomical
change may also be causative. Moreover, patients who seek refractive surgery are often contact
lens intolerant and may have preclinical dry eye before surgery. In addition, mechanical trauma
caused by the microkeratome suction ring to limbal Goblet cells has been suggested to play a
role in LASIKassociated
dry eye (Lenton and Albietz 1999). Diminished afferent input also
results in a decreased blinking rate, which appears to be involved in the pathogenesis of
LASIKassociated
dry eye (Toda et al. 2001)"""""""""""
I have found another source pointing to corneal nerve neuropathy
I am wanting to get more people aware of this problem because a lot more of us may have this than is realized, and we need to learn root causes instead of just only trying to treat what we can see on the surface (MGD/BLEPH/DES)
here is a paper from University of Helsinki in Helsinki, Finland describing corneal neuropathy after damage from surgery like lasik.
CORNEAL NERVES IN REFRACTIVE
SURGERY AND DRY EYE
heres the link to the main article. I put excerpts of the most important parts down below...
https://www.doria.fi/bitstream/handl...pdf?sequence=1
Here are some important excerpts
"Presumably, at least part of the symptoms of “LASIKassociated
dry eye” are derived from aberrantly regenerated and abnormally functioning corneal
nerves. Thus, they may represent a form of corneal neuropathy or “phantom pain” rather than
conventional dry eye."
""""Corneal refractive surgery (PRK and LASIK) severs corneal sensory nerves, impairing corneal sensitivity and function. Corneal nerve regeneration begins shortly, but the original fine nerve architecture may never be completely restored. Patients experience varying degrees of dry eye symptoms for a 1to 6month period following refractive surgery. Occasionally, extensive dry eye symptoms or even ocular pain may persist for years, with or without dry eye signs. On the other hand, patients may have clinical signs compatible with dry eye, but present with minimal or no symptoms."""""
'''''Secretion of tear fluid is also regulated by the corneal nerves
forming the afferent loop of the cornealacrimal
gland reflex arc. Several systemic and corneal
disorders as well as ocular surgery may damage the corneal nerves and impair their function.
Consequently, the regulation of epithelial cell and keratocyte metabolism and also tear
formation and corneal sensitivity are disturbed until innervation is restored.''''
"""""""changes in corneal curvature
may interfere with even tear distribution, but the mechanical rubbing due to the anatomical
change may also be causative. Moreover, patients who seek refractive surgery are often contact
lens intolerant and may have preclinical dry eye before surgery. In addition, mechanical trauma
caused by the microkeratome suction ring to limbal Goblet cells has been suggested to play a
role in LASIKassociated
dry eye (Lenton and Albietz 1999). Diminished afferent input also
results in a decreased blinking rate, which appears to be involved in the pathogenesis of
LASIKassociated
dry eye (Toda et al. 2001)"""""""""""
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