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Dartt and her team evaluated the eyes of 24 patients about to undergo LASIK at the Massachusetts Eye and Ear Infirmary. The patients were given a series of evaluations, including the Schirmer test with and without anesthesia, before and after surgery. Using a piece of paper on the corneal surface, the Schirmer test measures the amount of tears an eye is producing. Study subjects also filled out a dry eye questionnaire indicating their experience with dry eyes pre- and post-operatively.
The team discovered that if a patient had a presurgical tear production value greater than 20 mm of wetting of the Schrimer strip in 5 minutes, they were not likely to develop chronic dry eye syndrome. Patients who produced less tears were more likely to develop long-term dry eye syndrome.
I believe the following is the study referred to in this article:
Invest Ophthalmol Vis Sci. 2008 Jan;49(1):168-74.
Preoperative characteristics and a potential mechanism of chronic dry eye after LASIK.
Konomi K, Chen LL, Tarko RS, Scally A, Schaumberg DA, Azar D, Dartt DA.
Schepens Eye Research Institute, 20 Staniford Street, Boston, MA 02114, USA.
PURPOSE: To determine whether measurable preoperative characteristics predispose patients to chronic dry eye after laser in situ keratomileusis (LASIK).
METHODS: The study consisted of 24 eyes of 24 patients who underwent LASIK. Tear breakup time, Schirmer testing with and without anesthesia, rose bengal staining, central corneal sensitivity, nucleus-to-cytoplasmic ratio, and goblet cell density were evaluated 2 weeks before and 1 week, 3 months, and 9 months after surgery. Patients were classified into two outcome groups, the nondry-eye group (NDEG) and the chronic dry-eye group (CDEG), on the basis of dry eye status 9 months after surgery. The authors tested whether preoperative values of each parameter were associated with the development of chronic dry eye.
RESULTS: All parameters, except rose bengal staining, deteriorated significantly after surgery but returned to preoperative levels within 3 to 9 months. The CDEG had significantly lower preoperative Schirmer test values with and without anesthesia and were delayed in recovery after surgery in goblet cell density, rose bengal staining, Schirmer test values without anesthesia, and tear breakup time. Results of preoperative Schirmer tests without anesthesia positively correlated with tear breakup time 9 months after surgery.
CONCLUSIONS: Preoperative tear volume may affect recovery of the ocular surface after LASIK and may increase the risk for chronic dry eye.
dnew
Quote:
Dartt and her team evaluated the eyes of 24 patients about to undergo LASIK at the Massachusetts Eye and Ear Infirmary. The patients were given a series of evaluations, including the Schirmer test with and without anesthesia, before and after surgery. Using a piece of paper on the corneal surface, the Schirmer test measures the amount of tears an eye is producing. Study subjects also filled out a dry eye questionnaire indicating their experience with dry eyes pre- and post-operatively.
The team discovered that if a patient had a presurgical tear production value greater than 20 mm of wetting of the Schrimer strip in 5 minutes, they were not likely to develop chronic dry eye syndrome. Patients who produced less tears were more likely to develop long-term dry eye syndrome.
I believe the following is the study referred to in this article:
Invest Ophthalmol Vis Sci. 2008 Jan;49(1):168-74.
Preoperative characteristics and a potential mechanism of chronic dry eye after LASIK.
Konomi K, Chen LL, Tarko RS, Scally A, Schaumberg DA, Azar D, Dartt DA.
Schepens Eye Research Institute, 20 Staniford Street, Boston, MA 02114, USA.
PURPOSE: To determine whether measurable preoperative characteristics predispose patients to chronic dry eye after laser in situ keratomileusis (LASIK).
METHODS: The study consisted of 24 eyes of 24 patients who underwent LASIK. Tear breakup time, Schirmer testing with and without anesthesia, rose bengal staining, central corneal sensitivity, nucleus-to-cytoplasmic ratio, and goblet cell density were evaluated 2 weeks before and 1 week, 3 months, and 9 months after surgery. Patients were classified into two outcome groups, the nondry-eye group (NDEG) and the chronic dry-eye group (CDEG), on the basis of dry eye status 9 months after surgery. The authors tested whether preoperative values of each parameter were associated with the development of chronic dry eye.
RESULTS: All parameters, except rose bengal staining, deteriorated significantly after surgery but returned to preoperative levels within 3 to 9 months. The CDEG had significantly lower preoperative Schirmer test values with and without anesthesia and were delayed in recovery after surgery in goblet cell density, rose bengal staining, Schirmer test values without anesthesia, and tear breakup time. Results of preoperative Schirmer tests without anesthesia positively correlated with tear breakup time 9 months after surgery.
CONCLUSIONS: Preoperative tear volume may affect recovery of the ocular surface after LASIK and may increase the risk for chronic dry eye.
dnew
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