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  • Labial - ninor salivary gland transplantations to treat dry eyes

    Hi,
    What to do if every kind of Treatment and therapy of the dry eye and especially the MGD does not work and the damage to the whole
    ocular surface-corneas is increasing.
    The labial or minor salivary Gland - lip glands cluster transplantation was invented by Prof. Murube sen. in Madrid in the 90`s.
    Prof. Murube also invented the transplantation of the big salivary glands - submandibular glands to the eyes.
    So please do not mix-up the two totally different surgeries.
    The salivary big Glands - SMGT is a 5-7 hours taking difficult surgery. This surgery is only being performed by
    a Team in Germany and on in Pejing!

    The transplantation of the labial-lip glands cluster does take about 30 min.
    Unfortunately, most articles-studies on that surgery are not available for free in the net.
    So please google for -
    1. dry eye minor salivary gland transplantation Gupta, there you will find a PDF with Pictures.
    Do not be afraid by the bloody looking photos. Even a small injury does look bloody.

    2. Dry eye minor salivary gland transplantation dr Peter Raus

    The surgery is best being performed by using radio freqeuncy surgitron device from Ellman - NY.

    Patients that still do have a permanent aqueous tears supply of - Schirmer >=5mm, do benefit most. In such eyes, the mucin-fatty production of the
    Labial glands does substitute and complete the missing mucins and lipids very well.

    In South America they have transplanted the lip glands in totally dry eyes of Stevens Johnson-Lyell patients. Even these patients
    experienced an improvement of their ocular comfort and health.
    In order to have available two gland cluster sections, the surgeons have devited the lip cluster including the only one duct there.
    Obviously this frequently does damage the duct and the long term success rate is not so high.

    So the best way is tranfering the whole lower lip cluster under the upper eye lid in the worser-drier eye and the
    cluster from the upper lip into the better eye.

    So this surgery may help patients, that do still have some watery tears and sufferung from severe MGD and mucin deficiency.
    If the ocular surface situation does improve, that means less inflammation and irritations, then even the mucin producing
    goblet cells will return into the conjunctiva.
    Up to very recently, the majority of the Labial gland transplantations have been made to very dry eyes.
    So there are not many long term results available from patients, that suffered mainly from most severe MGD and mucin
    deficiency. The few patients that I do know told me, that after the labial transplantation they are able to work for 6-7 hours at the screen or
    driving with air conditioning on for several hours. Before the surgery they had been not able to work at all.

    It seems also necessary, that the surgeons do prevent the early mistakes and will improve the surgery techniques for even better long term results.
    I fear I am too old for that surgery. I am not a smoker, but for patients getting the glands at an age over 55-60 the Long lasting success is much lower.

  • #2
    Hi all,
    as I have wrote in the first thread, the minor salivary gland transplantation is the last good working option, if all other
    meibomian gland and dry eye therapies failed and the patients will have to deal the most difficult problems.

    Most articles on that technology are not available for free. Only the one from Gupta and these short ones:

    http://www.osnsupersite.com/view.aspx?rid=6529

    http://www.articlesbase.com/medicine...s-5015033.html


    as well as Google - radiosurgery aids salivary gland transplantations

    These labial - lip gland transplantations made it possible for some patients in spain and belgium stopping the sclerals
    wearing.
    By the way, these Labial gland patients are the only ones that have been able living without sclerals.
    If sclerals have been worn for 6-12 months, there will be no way back without lenses for the majority of patients.

    For younger people it is not a nice perspective being forced to wear sclerals for the next 50+ years.
    If too many meibomian glands have been destroyed, there are only the two options - sclerals or labial glands transplantation.

    The minor salivary gland transplantations are being performed by several teams in the world. Every good oculoplastic surgeon should be
    able to do it successfully. But only if they use the latest radiosurgery equipment-Ellmann Surgitron and the best proven techniques.
    Beside the inventing team in Madrid, two Teams in Brazil, two teams in Germany, two in India, one in Belgium, France an Argentina.

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    • #3
      peter56,

      I tested sclerals for two hours and I need decide if I will purchase it and try it or not. Even before I read your post I was afraid sclerals could make my eyes worse when not wearing them, and became dependent on them.

      From where did you get the information about sclerals destroying glands and people getting worse clinical signs after starting wearing them?

      Dou you know which are those two teams that perform the surgery with in Brazil?

      thanks!
      Last edited by bakunin; 10-May-2013, 17:26.

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