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I use quite a bit of other gels and drops, so most of the time there's a fair amount of "material" in my eyes besides tears. Some drops, including Restasis, seem to "consolidate" or concentrate the crud. There's some oil in R, from what I understand, so my theory is that the aqueous and the oils sort of separate. The liquid evaporates or drains out the punta, and blinking and gravity move the crud to the corners of the eyes where it collects and dries and looks gross.
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