Reported positive results for Ecabet Sodium Phase IIb for dry eye and initiated confi

[Rebecca Petris]

Rebecca- What is Panoptx?

Briefly... wraparound glasses that are very popular with the dry eye crowd.

Panoptx is a company in California that makes high-end sports eyewear. Certain of their products have proven very useful in managing symptoms of moderate to severe dry eye, for example helping people do activities they might not do otherwise (esp. outdoors). This is because they have an excellent wraparound shape and the best quality form-fitting vented foam lining of pretty much any eyewear out there. With chronic dry eye this is extremely helpful because it helps seal in moisture (natural and artificial tears), reduces excessive evaporation by preventing airflow over the eyes, and keeps out other irritants.

For many more details, please check out our eyewear page in the Encyclopedia. It includes links to some of the useful pages on the Panoptx website (which is a bit difficult to navigate if you're starting from scratch).

[katia]

to Kakinda

Hello Kakinda , sorry for the mispelling of your name, I'll correct this.
And thanks for your reply. I heard of Professor Baudouin, but I thought they also had a DES specialist at Rotchild. Sad they don't as I could probably get an appointment sooner at Rotchild than 15/20.

I have just another question: Do they sell cyclosporine in France also??? I started using it 2 months ago now and I am not sure I would like to stop now and loose the potential benefit of it. I say potential because with DES it is so difficult to know especially when you start it some med works or not. The pharmacist my parents approched in france looked schocked when they told her that it was used for eyes as they seems to only know the anti reject use of it.
Thanks again

[kakinda]

HI Katia,

maybe we could talk directly on this... send me a private email or send a message to Keratos if you want to know more about 15/20 and the specific cyclosporine they make there (or search the Keratos section on this board and post by "Kakinda" on "cyclosporine" where you may find you answers). You may send private messages to me in French if that's more convenient.

You misread me: I didn't say that Rotschild does not have a DE expert, I just said that 15/20 has a specialised team on DES. 3 hospitals produce cyclo in France and Rotschild is not one of them.

So why not try Rotschild and then try to get an appointment at 15/20 if you're not satisfied...

DE puts you in a strange position of having to explain - all the time - that many drugs have several uses besides the most common one: cyclosporine (graft rejection at 2%/ but DE as well in lower concentrations), doxycycline (antibiotic of course but rosacea, acnea and .... blepharitis, meibonianitis).

à +,
K

[Rojzen]

my old saw (about systemic pain treatment)

Just wanted to reference some older threads about pain treatment that may be of use to those here pondering how we can treat our pain without jeopardizing our corneas. . .

In these threads, some of us talked about using systemic pain treatments to soften the sensation in our eyes. . .I, for example, am blessed to have been accepted, some time ago, as a patient at the Johns Hopkins Pain Clinic in Baltimore, after the review panel there actually found merit in my petition. . .and recognized that our syndrome comes with real pain. . .

In a nutshell, I was shifted from amitriptyline, which had worked amazingly well to desensitive my ocular surface, to the newer drugs used for neurogenic pain. . .Never tried Neurontin, but did take a course of Tiagabene (sp?), and had it not caused me to be a little loopy, at work, I sense it would have been terrific. .

Anyway, please don't rule out the meds that treat neurogenic pain. . .The fact that much of our pain involves burning, stinging, and stabbing sensations is a cue to try neurogenic pain approaches. . Ultimately, the eye docs themselves may start helping us with these. . .Pending that, we should seek these out, where helpful, from internists and pain specialists. . .

Helping us out here is the fact that the autoimmune diseases (like SLE, RA. Sjogren's, and fibromyalgia) that sometimes give rise to the DES are often treated with a regimen that includes amitriptyline, to normalize the sleep cycle and truncate neurogenic pain responses. . .(Pain syndromes are most defintely exacerbated by poor quality sleep, btw. . ) Elavil (amitriptyline) is, e.g., often the first response a rheumatologist offers to fibromyalgia. . .

Anyway, pain meds and mechanical protection can be a terrific duo. . .To repeat points from older threads on eyewear, enclosing the abnormal eyes can, by itself, greatly extend TBUT, and extend the life of the cornea that is otherwise constantly barraged. . .