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Cyclosporine. Eye Drops. Loss of Corneal Sensitivity After LASIK.
LASIK Eye Surgeons from the University of Arizona, Arizona State University, Manicopa Hospital and Associated Retinal Consultants, in Phoenix, Arizona; from University of Illinois Eye and Ear Infirmary, Chicago, Illinois; and from Centro Láser, Santo Domingo, Dominican Republic; observed twenty two patients to determine whether 0.5% cyclosporine eye drops may be utilized to facilitate faster recovery of corneal sensitivity after LASIK.
The LASIK Eye Surgery researchers, including Dr Gholam A Peyman who “has a patent pending neuronal regeneration”; have concluded:
“Cyclosporine 0.5% was shown to significantly improve corneal sensitivity at 3 months after LASIK, which suggests that topical cyclosporine promotes enhanced corneal nerve regeneration.”1
The LASIK researchers from Phoenix, Chicago and Santo Domingo have also noted:
•“This prospective, randomized, single-center clinical study comprised 44 eyes of 22 patients scheduled to undergo bilateral LASIK.”
•“One eye was randomly assigned to receive cyclosporine drops twice daily for 3 months in addition to standard postoperative LASIK medication.”
•“Corneal sensitivity was measured using the Cochet-Bonnet esthesiometer in four areas outside and five areas inside the LASIK flap preoperatively and at 1 day, 1 week, 1 month, and 3 months postoperatively. Safety parameters of best spectacle-corrected visual acuity and the incidence of adverse events were also collected. “
•“For all four points outside the LASIK flap, normal corneal sensitivity was maintained throughout the study.”
•“In addition, no significant difference was found between the cyclosporine-treated eyes and the control eyes at these points.”
•“All points within the LASIK flap except the point closest to the hinge demonstrated profound corneal hypoesthesia at 1 day, 1 week, and 1 month postoperatively with no differences noted between the control and cyclosporine-treated eyes.”
•“These same points had statistically significantly greater corneal sensitivity in the cyclosporine group relative to the control group (P≤.011) at 3 months postoperatively.”
LASIK Eye Surgeons from the University of Arizona, Arizona State University, Manicopa Hospital and Associated Retinal Consultants, in Phoenix, Arizona; from University of Illinois Eye and Ear Infirmary, Chicago, Illinois; and from Centro Láser, Santo Domingo, Dominican Republic; observed twenty two patients to determine whether 0.5% cyclosporine eye drops may be utilized to facilitate faster recovery of corneal sensitivity after LASIK.
The LASIK Eye Surgery researchers, including Dr Gholam A Peyman who “has a patent pending neuronal regeneration”; have concluded:
“Cyclosporine 0.5% was shown to significantly improve corneal sensitivity at 3 months after LASIK, which suggests that topical cyclosporine promotes enhanced corneal nerve regeneration.”1
The LASIK researchers from Phoenix, Chicago and Santo Domingo have also noted:
•“This prospective, randomized, single-center clinical study comprised 44 eyes of 22 patients scheduled to undergo bilateral LASIK.”
•“One eye was randomly assigned to receive cyclosporine drops twice daily for 3 months in addition to standard postoperative LASIK medication.”
•“Corneal sensitivity was measured using the Cochet-Bonnet esthesiometer in four areas outside and five areas inside the LASIK flap preoperatively and at 1 day, 1 week, 1 month, and 3 months postoperatively. Safety parameters of best spectacle-corrected visual acuity and the incidence of adverse events were also collected. “
•“For all four points outside the LASIK flap, normal corneal sensitivity was maintained throughout the study.”
•“In addition, no significant difference was found between the cyclosporine-treated eyes and the control eyes at these points.”
•“All points within the LASIK flap except the point closest to the hinge demonstrated profound corneal hypoesthesia at 1 day, 1 week, and 1 month postoperatively with no differences noted between the control and cyclosporine-treated eyes.”
•“These same points had statistically significantly greater corneal sensitivity in the cyclosporine group relative to the control group (P≤.011) at 3 months postoperatively.”
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