From Eyeworld.org article Lenticule may beat LASIK in the dry eye arena:
Perhaps most importantly, he found that LASIK dry eye is a spectrum of disease states, which he divided into four categories: 1) neuropathic epitheliopathy, 2) tear fluid instability, 3) real aqueous tear deficiency due to nerve damage, 4) and neuropathic pain (phantom pain). Dr. Tuisku has found that most patients improve with respect to the first three categories of dry eye 6-12 months after LASIK. "But neuropathic pain is more complex," Dr. Tuisku said.
Regeneration of nerves can take 5 years, and the nerves regenerate differently than before, leading to what Dr. Tuisku calls "aberrant nerve fibers." "As nerve fibers grow back into the flap, they branch out," Dr. Reinstein said. "There tend to be more nerve endings than originally—double or triple nerve endings. Now a breeze of wind across the eye will feel like three times the amount of breeze, causing a sensation that the eyes are very dry."
Regeneration of nerves can take 5 years, and the nerves regenerate differently than before, leading to what Dr. Tuisku calls "aberrant nerve fibers." "As nerve fibers grow back into the flap, they branch out," Dr. Reinstein said. "There tend to be more nerve endings than originally—double or triple nerve endings. Now a breeze of wind across the eye will feel like three times the amount of breeze, causing a sensation that the eyes are very dry."
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