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Depression severity effects TBUT and Schirmers results ( basically causes dry eye!)

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  • Depression severity effects TBUT and Schirmers results ( basically causes dry eye!)

    This could mean an improvement ir due for some of us that are really suffering (and unknowingly depression is making our eyes worse.) (how to break the circle though, well thats another dilemma) its linked to my twitter but i know some don't like clicking links so il also copy and paste it here. feel free to contact me, there is a good community on twitter and a fast way to find these latest studies.

    paper reads: Dry Eye Disease in Patients with Newly Diagnosed Depressive Disorder.

    Tiskaoglu NS1, Yazıcı A1, Karlıdere T2, Sari E1, Oguz EY2, Musaoglu M3, Aslan S4, Ermiş SS1. Author information



    Psychiatric conditions and not just the treatments themselves might be involved in the pathophysiology of dry eye disease (DED). The aim of our study was to evaluate the association between depression and DED using objective and subjective tests in patients with newly diagnosed depressive disorder who were not using any medication which may help us to determine the sole effect of depression on dry eye. METHODS:

    Thirty-six patients from the psychiatry clinic with a new diagnosis of depressive disorder and 32 controls were included in the study. All met the Diagnostic and Statistical Manual IV criteria for depression. Beck Depression Inventory (BDI) was used to measure depression severity and the State-Trait Anxiety Inventory (Stai1, Stai2) for concomitant anxiety symptoms. The Ocular Surface Disease Index (OSDI) and Visual Functioning Questionnaires (VFQ25) were completed and used to confirm diagnosis of DED in conjunction with the tear break up time (TBUT), ocular surface vital dye staining, and Schirmer's test. RESULTS:

    The comparison of depressive and control groups revealed significantly lower Schirmer (20.3 9.9 vs. 25.7 9.3 mm) and TBUT (7.8 5.7 vs. 12.5 7.8 s) scores with a consistently higher Oxford score (1.8 3.2 vs. 0.2 0.4) in the depressive group. Although the parameters were affected in the depressive group, this did not influence OSDI (86.1 13.6 vs. 86.6 13.3) and VFQ25 (30.8 21.6 vs. 38.5 29.1) scores. In both groups, the three psychological test scores (Stai1-2 and BDI) were correlated to each other but none of these tests were correlated to OSDI, VRQL, Schirmer, TBUT, and Oxford staining scores. CONCLUSION:

    Our study shows a definite association between depression and DED. We feel that it is important that psychiatrists take this into account especially while prescribing antidepressants which may aggravate dry eye signs. KEYWORDS:

    Dry eye disease (DED); Schirmer; depression; tear break up time (TBUT)

    take care guys, and remember, never give up.

    People have recovered, so can we.