Hi all,
As most of you may know, oral tetracyclines seem to be frequently prescribed for cases of blepharitis, especially when Meibomian Gland Dysfuction is present. There seems to be some significant difference of opinion throughout medical literature however, as to which one is best. Also, the dose and duration seem to be important. Most doctors agree that tetracyclines exert anti-inflammatory properties at relatively low doses-long before they become effective as antibiotics. Still, some find better results (Like Dr. Latkany; who is generally underwhelmed with them in general) with pulse dosing at higher levels. I myself have taken oral minocycline at 50mg b.i.d.(twice a day) for about four months. I have not seen a significant benefit, but I think there definately is some. I wonder if switching to doxycycline would make a difference? That actually leads me to my question: has anyone found success with a particular antibiotic after trying others that didn't seem to work? I think that each analogue has slightly different effects on the body, so it's conceivable that one may work better than another, right?
As most of you may know, oral tetracyclines seem to be frequently prescribed for cases of blepharitis, especially when Meibomian Gland Dysfuction is present. There seems to be some significant difference of opinion throughout medical literature however, as to which one is best. Also, the dose and duration seem to be important. Most doctors agree that tetracyclines exert anti-inflammatory properties at relatively low doses-long before they become effective as antibiotics. Still, some find better results (Like Dr. Latkany; who is generally underwhelmed with them in general) with pulse dosing at higher levels. I myself have taken oral minocycline at 50mg b.i.d.(twice a day) for about four months. I have not seen a significant benefit, but I think there definately is some. I wonder if switching to doxycycline would make a difference? That actually leads me to my question: has anyone found success with a particular antibiotic after trying others that didn't seem to work? I think that each analogue has slightly different effects on the body, so it's conceivable that one may work better than another, right?
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