Oculeve Intranasal Tear Neurostimulator

[agrlds]

Hello guys,

Anybody knows what is going on with this (i have read) quite promising product? - Oculeve Intranasal Tear Neurostimulator.

Last news report trying to be aproved by FDA? July 2016... Any news after that?

https://www.eyeworld.org/neurostimul...-eye-treatment

http://www.oraclinical.com/articles/...eurostimulator

[MGD1701]

Yes, FDA approved the item, TrueTear, in April 2017. article,
Allergan Granted Marketing Authorization by the FDA for
TrueTear™, the First Intranasal Neurostimulating Device Proven to Temporarily Increase Tear Production

http://www.oraclinical.com/articles/allergan-granted-marketing-authorization-fda-truetear%E2%84%A2-first-intranasal-neurostimulating

Can anyone find the viedos?? How it works? For MGD too?

[agrlds]

Oh yes that's true... http://www.fiercebiotech.com/medical...or-gets-fda-ok

[h=1]
Can anyone find the viedos?? How it works? For MGD too?

https://m.youtube.com/watch?v=2oDiRVmFQNc

[MGD1701]

Thanks! I dont understand HOW it works for MGD/glands, can you?
Seems for tear problems??

[PhoenixEyes]

Thanks! I dont understand HOW it works for MGD/glands, can you?
Seems for tear problems??

Looking at that video about 1 minute in, the diagram shows 3 green "stimulation" dots that run down nerve pathways to the three tear film components, lacrimal gland / aqueous tear, meibomian glands / oils and the mucous membrane / goblet cells. I guess the suggestion is it might stimulate more oil and goblet cell production in addition to tears. It doesn't seem like they've yet quantified results from that side of things though, I suppose it's just easier to measure an improvement with lacrimal / aqueous using a bit of paper strip (schirmer) compared to measuring oil quantity / goblet cells. Maybe now they've got it out the door they'll do more studies on the other components.

I sometimes suffer from hormonal rhinitis so I guess I may not be able to do this =(
There's an article here that states some conditions it's contraindicated for (e.g. people prone to nosebleeds) and potential side effects (e.g. nasal irritation):

http://www.eyedolatryblog.com/2017/0...vice-that.html

[MGD1701]

Thanks PhoenixEyes.
Great item. Hopefully it works for MGD too. I do NOT aqueous problem.

[DryInDenver]

If I told you that at some point in the next year or two a device will be available that lets you jam a small rod up each nostril and use them to electrocute your face for up to 30 minutes per day would you be excited? Me too!

From someone that gags himself on a daily basis to get some moisture in his eyes, I think this product certainly looks interesting - more interesting at least than any drops that have come out since my eyes were blasted by a laser 4 years ago.

I look forward to giving this a try someday and hearing feedback from others that try it out.

Thanks for posting!

[MGD1701]

Here are more info/viedos

*Allergan TrueTear - A New Solution for Treating Dry Eye Disease (19.05.2017)
Precision Vision Edmond is proud to be the first vision care center in Oklahoma to prescribe TrueTear by Allergan.
TrueTear offers a no-drop, no-drug alternative that helps the body naturally produce tears.
If you suffer from Dry Eye Disease or MGD (meibomian gland disease), ask your optometrist if neurostimulation would be a good solution for you.
To schedule an appointment with Precision Vision Edmond, visit http://www.precisionvisionedmond.com/... or call 405-341-2062
https://www.youtube.com/watch?v=mbNPGg60Rpc

*Dry Eye and Glaucoma: Double Trouble, Mar 10, 2017
Interview with Richard A Lewis MD
https://googlecrawl.aao.org/intervie...double-trouble

[agrlds]

PhoenixEyes, MGD1701, DryInDenver,

I was in touch with Allergan. The product has just been released (few weeks) in the USA and currently just some physicians (specific clinics i guess) have access to the product. No estimate date to be released out of USA. The prodcut has to be prescribed by a physician iin order to get it.

How difficult can it be to get it...? Are you guys from USA?

http://www.truetear.com/

[pythonidler]

My doctor demo'd this on me in his office yesterday. It was quite uncomfortable, but I'm going to give it a try.

The device itself will be about $300 with insurance. You'll also have to buy disposable tips that cost $1 each and last 24 hours. Allergan will be shipping these out to consumers in September, but you'll need a doctor to prescribe it for you first.

[MGD1701]

Thanks for sharing pythonidler.
So it helps with MGD?
Please keep us informed the progress. Thanks!

[PhoenixEyes]

There's already a list of contraindications for the device but some on the Facebook groups have experienced another contraindication that may not yet be listed, people with trigeminal nerve issues. I also think they need to test if TMJ and rhinitis are also contraindicated.

Someone also shared this article which reviews Allergan's press article:

https://www.healthnewsreview.org/new...-eyes/?fref=gc

Experience 1 (won't post patient names since it's from closed groups)

28 June 2017 - I did a demo today and was minimally impressed. I have to say I hated sticking that probe up my nostrils. Did not feel great. So my experience was that every time I put it up my nose I sneezed. I never got it up my nose without sneezing. So I didn't buy it today. I couldn't tell whether my eyes were feeling wetter because of all the sneezing or if it was working.

29 June 2017 - Ok so 5 hrs after trying that device my trigeminal nerve is flaring up (I take gabapentin and Tegretol for it). My ear aches and my eye hurts, my face hurts all on the left side... (my Dr was afraid this might happen). I know that I was fine yesterday when I went in.

30 June 2017 - Still not better yet. So upset. That thing triggered my nerve. I had it under control for a couple months.

11 July 2017 - I'm having a constant earache every day. Be careful of this device if you have any issues with the trigeminal nerve. I'm not happy at all about this and feel like the neurologist should have never let me try that.

31 July 2017 - DO NOT buy this device without trying it first. I hated it and it hurt my TN. I'm better but it was about 1 month of pain.

Experience 2

2nd August 2017- I tried it in the drs office but it did not seems to produce tears but a lot of sneezing. I went ahead and did the trial being desperate with my recent dry eyes. $1000 plus $250 for the replacement tips. I charged it up at home but began to notice ear pain or fullness in one ear. I thought that maybe the sneezing caused a problem. It did not subside and went to Primary dr and he felt it was inner and not outer ear. Took a steroid pack- little improvement. Went to ENT before flying. He opened it up with spray but it still felt strange. Now the ear is finally beginning to more normal. Returned and got $1000 back. BEWARE!!!

The other contraindications already listed for the device:

This device is NOT approved for

• patients with implanted neurostimulator devices like pacemakers or wearable defibrillators
• patients under 22 years old or pregnancy (it's safety has not been studied at this time)
• use in water (a bath or shower), or around flammable gasses or shortwave devices
• patients with nasal or sinus surgery or untreated nasal infections
• patients with chronic or frequent nosebleeds, a bleeding disorder (eg, hemophilia), or another condition that can lead to increased bleeding
• patients with a known allergy to the hydrogel material the nasal tip is made from

[pythonidler]

Thanks for sharing pythonidler.
So it helps with MGD?
Please keep us informed the progress. Thanks!

My doctor says it stimulates both tear and oil production, but we'll see how well it works. He told me each "zap" gives you about 8 hours of tears and oil.

[hosanna13]

So I am not as hopeful for this nasalneural stimulator as I believe it just induces reflex tears due to pain. These 'crying' tears are more aqueous and have inflammatory cytokines compared to normal, basal tears. This is why your eyes turn red after a good crying session. I wish they had a lacrimal gland implant instead that could be programmed to provide enough electrical stimulation to secrete more basal tears. If anyone is able to get their hands on these devices, please let us know how it helps or doesn't!

[MGD1701]

Anyone has updates on this? Thanks for sharing!
Just found this interesting article (long one - read under: Neurostimulation),
seems these 7 (well-known) doctors in USA think highly of it.
https://crstoday.com/articles/dry-ey...new-therapies/