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Hi guys! Sorry for this really long post. Just wanted to share an amazing discovery I (think) I have made - lion’s mane eyedrops.
I am a post Lasik dry eye sufferer and I think my eyes have never been better post surgery than they are now (though, please also note that I’m on fish oil, hemp oil and evening primrose oil which have been helpful in the past, and I also did IRPL with was also helpful but I don’t think this is the full explanation since I’ve had relapses after these).
Lion’s mane is a fungus that when ingested can trigger release of nerve growth factor in the body. It is also used for wound healing and treating nerve damage. It can also promote outgrowth of neurites in cell culture:
https://pubmed.ncbi.nlm.nih.gov/23735479/
https://pubmed.ncbi.nlm.nih.gov/23510212/
https://pubmed.ncbi.nlm.nih.gov/22135902/
https://pubmed.ncbi.nlm.nih.gov/24266378/
https://www.dovepress.com/neurite-ou...xt-article-IJN
https://bmccomplementmedtherapies.bi...72-6882-13-261
There also an eyedrop out on the market now with recombinant nerve growth factor (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789413/ ) but it is immensely expensive.
So I decided to take the risk and manufacture and try my own lion’s mane eye drops. Please note that I have tried them only for about a month and cannot guarantee there are no adverse effects but so far so good (I will of course post here if I notice any adverse effects).
So, I buy this Lion’s mane powder:
https://hostdefense.com/products/lions-mane-powder
https://www.amazon.com/DEFENSE-Organ...fense+lion%27s +mane&qid=1619157041&sr=8-2
Then I cook it with distilled water. I don’t know the exact measures actually, I started with maybe 4 grams for 200 ml of fluid I think, but it was almost sticking to the pan after a while so I did a new batch where I added some more water gradually, maybe 500 ml in total, actually I don’t know exactly. I cooked for let’s say 20-30 minutes, let it cool off maybe for 30 minutes minimum, and then filtered it through a non-bleached coffee filter (I guess one could make it easier through using a funnel like this, though it’s not necessary: https://www.amazon.com/Corning-6220-...HDQ0G&pd_rd_r= 4ec9e53d-29f6-49b9-b9da-9f4db248d30c&pd_rd_w=GJXv9&pd_rd_wg=00kuM&pf_rd_p= 337be819-13af-4fb9-8b3e-a5291c097ebb&pf_rd_r=26ZQQB34RSSDPMQH9P9N&psc=1&re fRID=26ZQQB34RSSDPMQH9P9N, also I guess one could use a lab filter paper without additives for the filtration). Then I portioned it in 1 ml syringes of this kind:
https://www.amazon.com/1ml-Sterile-L...+1ml&qid=16191 56986&sr=8-3
I didn’t have any lids so after filling the syringe (with about 0,5 ml) i put it in its envelope again. Then I froze all the filled syringes in their envelopes and take one out and store in the fridge as eye drops and use a few times a day. When empty I put the syringe in another bag that I also freeze to reuse later - this might not be ideal from a sterility stand point but I do it anyway. The drops sting a slight bit but the sensation is very mild.
If one doesn’t want to cook an extract, I also found out there is aqueous extract in capsule form, have not tried it and don’t know if the material in the capsule could be harmful: https://mindnutrition.com/capsules/l...s#lg=1&slide=1
Please again notice that I don’t know if this would give long term adverse effects. Also, I don’t visit this forum (only to post something that I really think can be helpful), and unfortunately I don’t have time and energy to engage in any follow up posts, I have posted all the information I can provide above.
If you decide to proceed, good luck, and as they said in an email from a company growing lion’s mane that I contacted to get their input on how to do the mushroom extract - may the spores be with you! :-)
I am a post Lasik dry eye sufferer and I think my eyes have never been better post surgery than they are now (though, please also note that I’m on fish oil, hemp oil and evening primrose oil which have been helpful in the past, and I also did IRPL with was also helpful but I don’t think this is the full explanation since I’ve had relapses after these).
Lion’s mane is a fungus that when ingested can trigger release of nerve growth factor in the body. It is also used for wound healing and treating nerve damage. It can also promote outgrowth of neurites in cell culture:
https://pubmed.ncbi.nlm.nih.gov/23735479/
https://pubmed.ncbi.nlm.nih.gov/23510212/
https://pubmed.ncbi.nlm.nih.gov/22135902/
https://pubmed.ncbi.nlm.nih.gov/24266378/
https://www.dovepress.com/neurite-ou...xt-article-IJN
https://bmccomplementmedtherapies.bi...72-6882-13-261
There also an eyedrop out on the market now with recombinant nerve growth factor (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789413/ ) but it is immensely expensive.
So I decided to take the risk and manufacture and try my own lion’s mane eye drops. Please note that I have tried them only for about a month and cannot guarantee there are no adverse effects but so far so good (I will of course post here if I notice any adverse effects).
So, I buy this Lion’s mane powder:
https://hostdefense.com/products/lions-mane-powder
https://www.amazon.com/DEFENSE-Organ...fense+lion%27s +mane&qid=1619157041&sr=8-2
Then I cook it with distilled water. I don’t know the exact measures actually, I started with maybe 4 grams for 200 ml of fluid I think, but it was almost sticking to the pan after a while so I did a new batch where I added some more water gradually, maybe 500 ml in total, actually I don’t know exactly. I cooked for let’s say 20-30 minutes, let it cool off maybe for 30 minutes minimum, and then filtered it through a non-bleached coffee filter (I guess one could make it easier through using a funnel like this, though it’s not necessary: https://www.amazon.com/Corning-6220-...HDQ0G&pd_rd_r= 4ec9e53d-29f6-49b9-b9da-9f4db248d30c&pd_rd_w=GJXv9&pd_rd_wg=00kuM&pf_rd_p= 337be819-13af-4fb9-8b3e-a5291c097ebb&pf_rd_r=26ZQQB34RSSDPMQH9P9N&psc=1&re fRID=26ZQQB34RSSDPMQH9P9N, also I guess one could use a lab filter paper without additives for the filtration). Then I portioned it in 1 ml syringes of this kind:
https://www.amazon.com/1ml-Sterile-L...+1ml&qid=16191 56986&sr=8-3
I didn’t have any lids so after filling the syringe (with about 0,5 ml) i put it in its envelope again. Then I froze all the filled syringes in their envelopes and take one out and store in the fridge as eye drops and use a few times a day. When empty I put the syringe in another bag that I also freeze to reuse later - this might not be ideal from a sterility stand point but I do it anyway. The drops sting a slight bit but the sensation is very mild.
If one doesn’t want to cook an extract, I also found out there is aqueous extract in capsule form, have not tried it and don’t know if the material in the capsule could be harmful: https://mindnutrition.com/capsules/l...s#lg=1&slide=1
Please again notice that I don’t know if this would give long term adverse effects. Also, I don’t visit this forum (only to post something that I really think can be helpful), and unfortunately I don’t have time and energy to engage in any follow up posts, I have posted all the information I can provide above.
If you decide to proceed, good luck, and as they said in an email from a company growing lion’s mane that I contacted to get their input on how to do the mushroom extract - may the spores be with you! :-)
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